How an RNA polymerase performs in IVT depends on many factors, like capping strategy. Not every enzyme suits every template design. In this video, Christopher Warner, PhD, Director of Analytical Development at Primrose Bio, walks through three Prima RNApols® polymerases. Each one is built with unique benefits:
- Prima Cap AU, for AU-capped and self-amplifying RNA
- Prima Cap AG, for AG-capped RNA
- Prima 7 Pro, for existing T7 promoter workflows with no redesign needed
Chris covers capping efficiency, double-stranded RNA (dsRNA) levels and cumulative immunogenicity, the factors that set these polymerases apart. Watch the video to match the right polymerase to your workflow.
Christopher Warner, PhD
Director of Analytical Development
Chris Warner, PhD, is Director of Analytical Development at Primrose Bio, where he leads analytical efforts supporting the development and characterization of Prima RNApols® enzymes. Since joining the company in 2019, he has supported analytical development, protein characterization, and regulatory CMC activities across internal and partnered programs.
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