Insights / Resource Center
Resources
Presentations
Scientific Posters

Events
Antibody Engineering & Therapeutics US 2025
December 14–17, Primrose Bio presents at Antibody Engineering & Therapeutics 2025 with Diane Retallack, PhD, sharing advances in rapid, robust antibody screening.
Primrose Bio at PEGS Europe 2025: Accelerating Protein Therapeutics with Pfast™
November 11–13, Primrose Bio presents at PEGS Europe 2025 with Diane Retallack, PhD, sharing insights on Pfast™ protein expression.
Primrose Bio at the 13th International mRNA Health Conference: Innovation on Display in Berlin
November 11–13, Primrose Bio to exhibit and present at the 13th International mRNA Health Conference, taking place in Berlin. This annual gathering of mRNA leaders brings together cutting-edge research and industry insight.
Presentations
No Compromises: Engineered RNA polymerases for high quality, low-cost mRNA manufacturing
Achieving High Quality Efficient mRNA Synthesis
Pfast™ Protein Expression
Achieving High Quality Efficient mRNA Synthesis
Scientific Posters
Presented at TIDES USA 2025: Prima RNApols™ ExTend: rewriting the rules of long mRNA manufacturing
ABSTRACT: The success of mRNA COVID-19 vaccines has transformed the therapeutic landscape, accelerating the development of mRNA-based treatments across diverse applications. While in vitro...
Presented at TIDES USA 2025: Advancing mRNA therapeutics with high performance RNA polymerases
ABSTRACT: RNA has emerged as a critical tool in modern biotechnology and therapeutics, with applications ranging from vaccine development to gene therapy. mRNA is synthesized by in vitro...
Presented at PEGS US 2025: High-Throughput Expression and Purification of Untagged RNA Polymerase Variants: Advancements in the Pfenex Expression Technology® Platform
ABSTRACT: Primrose Bio's Pfenex Expression Technology® (Pfenex) platform has established itself as a robust, scalable solution for recombinant protein production, as evidenced by its role in six...
Case Studies
Pfenex

Recombinant Erwinia Asparaginase Production
Acute lymphoblastic leukemia (ALL) is the most common type of cancer in children. Lymphoblastic lymphoma (LBL) is a rare, fast-growing, aggressive subtype of non-Hodgkin’s lymphoma most often seen in teenagers and young adults.
Pfenex

Production of disulfide-rich cow knob domain antibodies: picobodies™
About 10% of cow antibodies have exceptionally long heavy chain CDR3 regions, including a stalk and knob region.
Pfenex
Multimeric vhh nanobody expression
Pfenex
Fab antibody fragment titer improvement

Anti-IL-4 Conjugate Vaccine Prepared with PeliCRM197 is More Immunogenic than KLH Analog

Comparable Immunogenicity Observed in Peptides Coupled to PeliCRM197 and KLH in a Murine Model
In this case study, 3 peptides (peptides #5, #6, and #7) directed to one therapeutic target were conjugated to either CRM197 (a non-toxic diphtheria toxin mutant) produced with Pfenex Expression Technology® or to KLH (keyhole limpet hemocyanin).





