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Scientific Posters

Case Studies

Success Stories

Events

Presentations

Accelerating Antibody Screening with a Scalable Protein Expression Platform

Diane Retallack, PhD at the PepTalk: The Protein Science and Production Week, January 2026

Pfast™ Protein Expression: A Rapid, Robust Solution for Accelerating Antibody Screening

Diane Retallack, PhD at the Antibody Engineering & Therapeutics, December 2025

Achieving High Quality Efficient mRNA Synthesis for streamlined and cost-effective manufacturing

Helge Zieler, PhD and Khaled Yamout at a webinar with Nucleic Acid Insights

No Compromises: Engineered RNA polymerases for high quality, low-cost mRNA manufacturing

Helge Zieler, PhD at the 13th International mRNA Health Conference in Berlin, November 2025.

Engineered Enzymes Powering the Future of mRNA Therapeutics

Sabrina Baffert at the 13th International mRNA Health Conference in Berlin, November 2025.

Pfast™ Protein Expression: A Rapid, Robust Solution for Accelerating Biotherapeutic Screening

Russell Coleman at a webinar with Antibody Engineering & Therapeutics, May 2025

Scientific Posters

Case Studies

Pfenex

Recombinant Erwinia Asparaginase Production

Acute lymphoblastic leukemia (ALL) is the most common type of cancer in children. Lymphoblastic lymphoma (LBL) is a rare, fast-growing, aggressive subtype of non-Hodgkin’s lymphoma most often seen in teenagers and young adults.

Pfenex

Production of disulfide-rich cow knob domain antibodies: picobodies™

About 10% of cow antibodies have exceptionally long heavy chain CDR3 regions, including a stalk and knob region.

Pfenex

Multimeric vhh nanobody expression

VHH single domain antibodies readily express in the Pfenex Expression Technology®. Expression and enrichment of a variety of VHH specificities facilitated early drug development.

Pfenex

Fab antibody fragment titer improvement

A partner was developing a Fab fragment to quickly neutralize a therapeutic substrate. Their E. coli platform generated low Fab titer and meaningful supply was needed for clinical development.
Pelicrm197

Anti-IL-4 Conjugate Vaccine Prepared with PeliCRM197 is More Immunogenic than KLH Analog

Anti-interleukin 4 (IL-4) conjugate vaccines consist of IL-4 chemically coupled to a carrier protein. Immunizations with these vaccines, in combination with an adjuvant, elicit the production of polyclonal anti-IL-4 neutralizing antibodies in mice.
Pelicrm197

Comparable Immunogenicity Observed in Peptides Coupled to PeliCRM197 and KLH in a Murine Model

In this case study, 3 peptides (peptides #5, #6, and #7) directed to one therapeutic target were conjugated to either CRM197 (a non-toxic diphtheria toxin mutant) produced with Pfenex Expression Technology® or to KLH (keyhole limpet hemocyanin).

Success Stories

Manufacturing of RYLAZE utilizes Pfenex Expression Technology

Hear from the senior director for the biologics development team at Jazz Pharmaceuticals about the RYLAZE manufacturing process.

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