by Primrose Bio | Dec 14, 2025 | Scientific Posters
ABSTRACT: A platform-based approach leveraging the Pfenex Expression Technology® was developed for implementing screening through lead optimization of novel ADCs. As an example of the workflow, an Anti-GPCR VHH therapeutic candidate modified to include a single ncAA... 
by Primrose Bio | Nov 11, 2025 | Scientific Posters
ABSTRACT: The field of mRNA therapeutics is rapidly developing across a wide range of applications, including infectious diseases, rare disorders, protein replacement, and cancer immunotherapy. Central to the production of mRNA is in vitrotranscription (IVT), a method... 
by Primrose Bio | Nov 11, 2025 | Scientific Posters
ABSTRACT: Amber suppression technology has matured over the last 25 years, enabling incorporation of non-canonical amino acids (ncAAs) that allow targeted conjugation and expanded therapeutic functionality. Despite its potential, implementation has been limited by... 
by Primrose Bio | Jun 11, 2025 | Scientific Posters
ABSTRACT: The success of mRNA COVID-19 vaccines has transformed the therapeutic landscape, accelerating the development of mRNA-based treatments across diverse applications. While in vitro transcription (IVT) is a powerful method for mRNA production, its efficiency... 
by Primrose Bio | May 20, 2025 | Scientific Posters
ABSTRACT: RNA has emerged as a critical tool in modern biotechnology and therapeutics, with applications ranging from vaccine development to gene therapy. mRNA is synthesized by in vitro transcription using single-subunit RNA polymerases, whose performance directly... 
by Primrose Bio | May 12, 2025 | Scientific Posters
ABSTRACT: Primrose Bio’s Pfenex Expression Technology® (Pfenex) platform has established itself as a robust, scalable solution for recombinant protein production, as evidenced by its role in six commercially approved products. Integrating sophisticated...